Connexin gap junctions and hemichannels in modulating lens redox homeostasis and oxidative stress in cataractogenesis
Y Quan, Y Du, Y Tong, S Gu, JX Jiang - Antioxidants, 2021 - mdpi.com
… the important roles of connexin channels in the lens under … -forming gap junction intercellular
communication (GJIC) and … (FGF)-mediated increase of the number of open gap junction …
communication (GJIC) and … (FGF)-mediated increase of the number of open gap junction …
Insights into bone morphogenetic protein—(BMP-) signaling in ocular lens biology and pathology
… , p38 and the extracellular signal-regulated kinase (ERK), C-… FGF signaling is required for
lens fiber differentiation, FGFs … Gap junction-mediated intercellular coupling (GJIC) is higher …
lens fiber differentiation, FGFs … Gap junction-mediated intercellular coupling (GJIC) is higher …
Lens connexin channels show differential permeability to signaling molecules
… contribute to the regulation of the intercellular communication necessary for normal growth of
the … In addition, gap junction-mediated Ca 2+ signaling has been observed in cultured lens …
the … In addition, gap junction-mediated Ca 2+ signaling has been observed in cultured lens …
Dual function of TGFβ in lens epithelial cell fate: implications for secondary cataract
BA Boswell, A Korol, JA West-Mays… - Molecular biology of the …, 2017 - Am Soc Cell Biol
… Assessing the rate at which TGFβ stimulates extracellular signal–regulated kinase (ERK) …
fact that lens cells endogenously produce FGF and that FGF is a major inducer of pERK in the …
fact that lens cells endogenously produce FGF and that FGF is a major inducer of pERK in the …
Cell transdifferentiation in ocular disease: Potential role for connexin channels
… building blocks of gap junctions (GJs) [39]. Gap junction intercellular communication (GJIC) …
, capsular scarring after cataract lens removal and intraocular lens implant. Chick embryonic …
, capsular scarring after cataract lens removal and intraocular lens implant. Chick embryonic …
Connexin43 and connexin50 channels exhibit different permeability to the second messenger inositol triphosphate
V Valiunas, TW White - Scientific Reports, 2020 - nature.com
… Robinson, ML An essential role for FGF receptor signaling in lens development. Semin Cell
… proteins regulates gap junction-mediated intercellular communication in lens cells. Mol Biol …
… proteins regulates gap junction-mediated intercellular communication in lens cells. Mol Biol …
[HTML][HTML] Lens connexin channels have differential permeability to the second messenger cAMP
… to the intercellular communication necessary for normal lens growth. Gap junctions were …
Detection of gap-junction–mediated movement of cAMP between cells was accomplished …
Detection of gap-junction–mediated movement of cAMP between cells was accomplished …
Single-Cell RNA Sequencing of Wild-Type and Connexin 50 Knockout Postnatal Lenses and Proposed Mechanisms of Impaired Epithelial Proliferation
AA Giannone - 2022 - search.proquest.com
… extracellular signal-regulated protein kinase 1/2 FGF … Gap junction channels are intercellular
communication channels … to important signaling pathways, such as FGF and PI3-K/Akt (A.-…
communication channels … to important signaling pathways, such as FGF and PI3-K/Akt (A.-…
Jack of all trades, master of each: the diversity of fibroblast growth factor signalling in eye development
N Makrides, Q Wang, C Tao, S Schwartz… - Open …, 2022 - royalsocietypublishing.org
… In the lens, we showcase the dynamics of FGF signalling in … , FGF-MAPK also promotes gap
junction-mediated cell … a single intercellular communication pathway like FGF signalling can …
junction-mediated cell … a single intercellular communication pathway like FGF signalling can …
Experimental models for posterior capsule opacification research
IM Wormstone, JA Eldred - Experimental eye research, 2016 - Elsevier
… rabbit lens is similar in size to a human lens and can accommodate an IOL designed for human
implantation. The in vivo rabbit model has played a role … EGF, HGF, FGF, KGF and TGFβ …
implantation. The in vivo rabbit model has played a role … EGF, HGF, FGF, KGF and TGFβ …